What Is JUVÉDERM™ Injectable Gel?

Juvéderm™ is a smooth consistency gel made of hyaluronic acid—a naturally occurring substance in your skin that helps to add volume and hydration. Your healthcare professional eases Juvéderm™ injectable gel under the skin to instantly restore your skin's volume and smooth away facial wrinkles and folds, like your “smile lines” or “parentheses” (nasolabial folds—the creases that run from the bottom of your nose to the corners of your mouth).

Juvéderm™ provides a smooth, natural look and feel—so everyone will notice (but no one will know)! In fact, studies show superior results of Juvéderm™ compared to a collagen-based dermal filler.^†

• Almost 90% of all study volunteers who were treated with both Juvéderm™ injectable gel and another dermal filler^† preferred Juvéderm™!
• Juvéderm™ injectable gel is the first FDA-approved hyaluronic acid dermal filler that is proven to be safe and effective for persons of color.

Benefits of JUVÉDERM™ Injectable Gel.

Hyaluronic acid dermal fillers like Juvéderm™ injectable gel offer a safe and effective nonsurgical option for smoothing facial wrinkles and folds. In fact, they are the fastest growing nonsurgical aesthetic procedure in the United States according to the American Society of Aesthetic Plastic Surgery.¹ But all dermal fillers are not the same!

Choosing JUVÉDERM™ injectable gel makes a difference:

• Juvéderm™ is the ONLY hyaluronic acid (HA) filler FDA approved* to last up to 1 year. Our unique manufacturing process provides a high concentration of cross-linked hyaluronic acid for long-lasting results. It also creates a smooth consistency gel that flows easily into the skin and provides a smooth, natural look and feel—so everyone will notice (but no one will know)! Only Juvéderm™ is so smooth—other hyaluronic acid fillers currently on the market are made of granular consistency gels.**
• A "next-generation" filler: Juvéderm™ is a “next-generation” non-animal dermal filler that is made from hyaluronic acid—a naturally occurring substance that plays a vital role in hydrating your skin and replenishing its natural volume. No allergy skin tests are needed prior to receiving treatment.

How JUVÉDERM™ Works

Juvéderm™ injectable gel dermal filler is a nonsurgical, physician-administered treatment. Your healthcare professional eases Juvéderm™ under the skin using a fine needle to augment, or fill, the soft tissue of the dermis—the dense inner layer of skin beneath the epidermis—to add volume and diminish wrinkles and folds. Juvéderm™ injectable gel is great for your "laugh lines," "smile lines" or "parentheses" (nasolabial folds), or "marionette lines" (oral commissures).

Juvéderm™ is a "next-generation" filler. It is made from hyaluronic acid—a naturally occurring substance in your skin that helps to hydrate and add volume. Hyaluronic acid may diminish with age, contributing to the formation of wrinkles and folds. Juvéderm™ injectable gel works to correct this by restoring hyaluronic acid in your skin, helping to smooth wrinkles and folds.

What to Expect During Treatment

Because Juvéderm™ injectable gel is a simple, nonsurgical wrinkle treatment, there is minimal recovery or downtime. So you can make an appointment to stop by your healthcare professional's office for treatment on the way home from work or the gym, or even while the kids are at soccer practice—and get right back to your life. Here's what to expect when you visit your healthcare professional's office for treatment. (Please note that although this experience is typical, the routine at your healthcare professional's office may be different.)

Before you go: Some doctors recommend that you avoid any medications that can prolong bleeding, such as aspirin and non-steroidal anti-inflammatories (NSAIDs), for at least a week prior to treatment in order to reduce the risk of bruising and bleeding at the injection site. Ask your healthcare professional what he or she recommends.

When you arrive: If this is your first visit, your healthcare professional will ask about your medical history, including any allergies you may have or medications you may take, and will tell you more about wrinkle treatment with Juvéderm™. Juvéderm™ injectable gel does not require an allergy test.

Determining your treatment needs: Your healthcare professional will examine the soft tissue of your face to assess the depth of wrinkles and folds to determine your treatment. Juvéderm™ injectable gel is available in two formulations—Juvéderm™ Ultra for versatility in contouring and volumizing facial wrinkles and folds, and Juvéderm™ Ultra Plus, a robust formulation for volumizing and correcting deeper folds and wrinkles. This allows your healthcare professional to better tailor treatment to your unique needs. They may even take pre-treatment photographs so you can see the difference after treatment!

Before the procedure: Although anesthesia is not required, your healthcare professional may use topical or injectable anesthesia to numb the treatment area first.

The procedure: Your healthcare professional will ease the Juvéderm™ injectable gel under your skin to augment, or fill, wrinkles and folds. Following the injection, your healthcare professional may gently massage the treated areas. The procedure is quick and easy. The injection itself usually takes only about 15 minutes.

After the procedure: With Juvéderm™, there is minimal recovery or downtime.

For the first 24 hours following treatment, you should avoid strenuous exercise, excessive sun or heat exposure, and consumption of alcoholic beverages in order to help minimize the risks of temporary redness, swelling, and/or itching at the treatment sites. After the treatment, some temporary injection-related reactions may occur, including redness, pain, firmness, swelling, and bumps. Studies have shown that these are usually mild to moderate in nature and clear up on their own in 7 days or less. If you experience swelling at the injection site, you can apply an ice pack for a brief period. Your healthcare professional will tell you when makeup may be applied after your treatment.

Seeing results: You should see an immediate improvement in the treatment areas. Most patients need one treatment to achieve optimal wrinkle smoothing. And one treatment could smooth your lines and wrinkles for up to 1 year! However, results may vary and correction is temporary. Supplemental “touch up” treatments may be required to achieve and maintain optimal results.

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WHAT IS BOTOX^® COSMETIC?

BOTOX^® Cosmetic is a simple, nonsurgical, physician-administered treatment that can temporarily smooth moderate to severe frown lines between the brows in people from 18 to 65 years of age. It is the only treatment of its type approved by the Food and Drug Administration (FDA).

One 10-minute treatment—a few tiny injections—and within days there's a noticeable improvement in moderate to severe frown lines between the brows, which can last up to 4 months. Results may vary.

BOTOX^® Cosmetic is a purified protein produced by the Clostridium botulinum bacterium, which reduces the activity of the muscles that cause those frown lines between the brows to form over time.

In 2005, almost 3.3 million procedures were performed with FDA-approved BOTOX^® Cosmetic.

WHY GET TREATED WITH BOTOX^®
COSMETIC?
When it comes to selecting a physician-administered aesthetic treatment, chances are you’ll want proof, not just claims. The proof for BOTOX^® Cosmetic is in the numbers.

• In clinical trials, nearly 90% of men and women surveyed rated the improvement in the appearance of frown lines between their brows as moderate to better 1 month after treatment. Results vary.
• Results can last for up to 4 months, and may vary.
• BOTOX^® Cosmetic was approved by the Food and Drug Administration (FDA) in 2002 for the temporary treatment of moderate to severe frown lines between the brows in people ages 18 to 65, and almost 3.3 million procedures were performed in 2005 alone.
• The American Society for Aesthetic Plastic Surgery ranked BOTOX^® Cosmetic as the most popular physician-administered aesthetic procedure in the United States for the fourth year in a row (surgical and nonsurgical combined).

WHAT TO EXPECT AT THE DOCTOR'S OFFICE?

Before you try and schedule your first BOTOX^® Cosmetic treatment consultation, you probably have some questions, such as: How long will it take? How long will the results last? Will it hurt? Will I still be able to make facial expressions?

Here's what you might expect at the doctor's office from the moment you arrive until your procedure is done. (Please note that although this experience is typical, the routine at your doctor's office may be different.)

The day of your appointment. Allow time before your appointment for filling out forms and for consulting with the doctor or a member of his or her staff. If it's your initial visit, you may first meet with your doctor personally or a staff member. Many doctors have on-staff licensed aestheticians or nurses who are trained in skin care and skin care procedures who can answer many of your questions.

You may also be asked about your expectations for treatment and if you have any allergies or any condition that wouldn't make you a good candidate for BOTOX^® Cosmetic. (See the full prescribing information for more details.)

Before the procedure. You'll probably be seated in a reclining chair, much like you find in a dentist's office. No anesthesia is required, although your doctor may choose to numb the area with a cold pack or anesthetic cream.

The procedure. Your doctor will determine where to administer the injections by examining your ability to move certain muscles in your brow area. The entire BOTOX^® Cosmetic injection procedure takes approximately 10 minutes.

For more information, read about the injection process.

After the procedure. There's no recovery time needed. You're ready to get on with your day! The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness, and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis, or Lambert-Eaton syndrome may be at increased risk of serious side effects.

Seeing results. Within days, you may notice an improvement in the moderate to severe frown lines between your brows that can last up to 4 months. Results may vary.